No one will argue that discovery antibiotics made a breakthrough in medicine and allowed to save many lives. But viruses and bacteria mutate, develop resistance to drugs, and the effectiveness of the latter is significantly reduced. And the fight against some infectious diseases with existing medicines is no longer possible.
World Health Organization reports 2010 infection data tubercle bacillusresistant to most antibiotics. More than 500 thousand people fell ill, a third of them died. Margaret Chen, WHO Director, said that the widespread use of pathogens leads to unreasonably frequent use of medicines.
German researchers Institute of Cell Therapy and Immunology Fraunhofer announced the discovery of antimicrobial peptideskilling most microorganisms. In the development process, emphasis has been placed on creating sequences of less than 20 amino acids. Such peptides carry amino acid residues with a positive charge, therefore, they are attracted to the cell membranes of pathogenic microorganisms with a negative charge and penetrate into them.
Bactericidal effectcoming in a few minutes, is achieved by a concentration that is ten times lower than that of traditional antibiotics. Another of the most important advantages is the safety of such peptides - they act selectively and do not damage healthy cells.
The use of antimicrobial peptides in the food industry can significantly boost the economies of countries, since the losses from food contamination by various bacteria are enormous. And adding them in the manufacture of food products will significantly increase the shelf life. Moreover, the tests did not show any harmfulness or allergenicity data connections.
In the near future, the chief project manager Dr. Schubert hopes to begin testing the effectiveness of antimicrobial peptides against infections in animals.