In 1 tablet of paracetamol 125, 250 or 500 mg.

Crospovidone, magnesium stearate, polyacrylate dispersion, mannitol, aspartame, silicon dioxide, banana flavor, - as auxiliary substances.

Release form

Dispersed (soluble) tablets in the oral cavity 125, 250 and 500 mg. Long-acting tablets of 500 mg.

Pharmachologic effect

Analgesic, antiperetic.

Pharmacodynamics and pharmacokinetics


Paracetamol- non-narcotic analgesicand antipyretic. It has an unexpressed anti-inflammatory effect due to the suppression of prostaglandin synthesis.

Antipyreticthe action is associated with the effect on the thermoregulatory center. It inhibits the synthesis of enzymes related to pain and temperature of central origin. It has no peripheral effect.


Fully absorbed by ingestion. The maximum concentration in the blood is determined after 30-60 minutes. The maximum blood concentrations of a prolonged form of the drug are determined after 3 hours, and the effect lasts 10-12 hours.
It is well distributed over all tissues, binds to blood proteins in a small amount.

It is metabolized in the liver by conjugation with sulfuric (when taking high doses) and glucuronic acid. A toxic intermediate metabolite can form, which is quickly neutralized and excreted by the kidneys. In children, metabolic processes have features: almost all paracetamol is metabolized and toxic metabolites are not formed, therefore, in case of an overdose of the drug, liver damage is very rare.

Excreted in urine - 90% of the dose within 24 hours. The elimination half-life is 2 hours, and the prolonged form is 10 hours.

Indications for use

  • headache, migraine;
  • algodismenorea;
  • myalgia;
  • toothache, also with teething;
  • neuralgia;
  • trauma pain;
  • fever after vaccination for infectious diseases (ARVI, ARI), with otitis media, sinusitis.


  • hypersensitivity to the drug;
  • phenylketonuria;
  • hepaticand renal failure;
  • congenital deficiency of glucose-6-phosphate dehydrogenase.

Side effects

  • itchy skin hivesrash on the skin and mucous membranes,Quincke's edema;
  • nausea, pain in the stomach, increased liver enzymes;
  • hypoglycemia;
  • hemolytic anemia, anemiawith prolonged use - aplastic anemia, thrombocytopenia, leukopenia, agranulocytosis;
  • when used in large doses, the nephrotoxic effect of the drug is manifested interstitial nephritis, renal colic.

Rapidol, instructions for use (Method and dosage)

The tablets are taken orally, having previously dissolved in a small amount of water (for children under 6 years of age) or absorbed in the mouth (adults and children over 6 years of age). Tablets should be taken 1-2 hours after a meal, between meals should be observed a break of at least 4 hours.

Dosage is calculated per kg of weight. Children weighing up to 40 kg are prescribed 80 mg / kg of weight per day, with a weight of 50 kg or more, as well as adults - 4 g per day. In this regard, children 3-6 months. more rational to take Rapidol 125 - 1 tablet after 6 hours, not more than 3 tablets per day. Children 18-24 months old You can give up to 6 tablets per day of the same dosage every 4 hours. At an older age from 2 to 15 years, Rapidol 250 is prescribed from 4 to 12 tablets per day in accordance with the weight: with a weight of 13-20 kg - 1 g of the drug per day, 21-25 kg -1.5 g, 26-40 kg - 2g, 41-50kg - 3g. Adults take Rapidol 500 every 4 hours, but not more than 4 g per day.

With severe pain and fever You can take 2 tablets of 500 mg at once.
Dispersed tablets can be used in children from 3 months, and a retard (prolonged) form in children from 7 years of age and adults. Rapidol Retardapply with an interval of 12 hours. Children weighing up to 40 kg take 1-2 tablets every 12 hours, and children from 12 years old and adults take 1-4 tablets.


Overdose is manifested by symptoms: lack of appetite, vomiting, nauseapallor of the skin. After 3-5 days, toxic liver damage with symptoms liver failure. Treatment method: hospital admission, determination of blood level paracetamolantidote administration M-aceticysteinesymptomatic treatment.


Hepatotoxicity of the drug is enhanced with the simultaneous administration of anticonvulsants, Rifampicin, barbiturates. Alcohol intake also enhances hepatotoxicity. Enhances the effect indirect coagulants. Barbiturates reduce the antipyretic effect of Rapidol. Metoclopramide increases the absorption of paracetamol, and Cholestyramine lowers.

Terms of sale

Without recipe.

Storage conditions

At temperatures up to 25 C.

Shelf life

2 years.


Matches for ATX Level 4 code:PhenacetinCombigrippChlorphenamineColdflouKalpolFairwexPanadol ExtraPanadol for childrenPanadolSolpadeinEfferalganMilistanColdrex MaxgrippColdrex HotremColdrexAnti influenzaUnispazPentalgin PlusMaxicoldPerfalgan

Paracetamol, Efferalgan.

Reviews of Rapidol

The usual tablet form of drugs causes difficulty in swallowing, especially in children. However, not all drugs can be crushed or powdered, since the effectiveness of the drug is reduced. But this does not apply to the dispersed form of tablets - they need to be absorbed in the mouth (under the influence of saliva, they quickly dissolve) or can be dissolved in a small amount of water, juice or milk. In this case, we are talking about Rapidol. Many parents respond positively to the drug Rapidol for children, which is easily soluble in any liquid and does not cause problems when taken. For adults, this form of paracetamol is also convenient: you do not need to drink it with water, since the tablet quickly dissolves in the mouth, immediately enters the bloodstream without exerting a negative effect on the gastric mucosa, it acts quickly - the analgesic effect is achieved after 10 - 20 minutes. The tablet does not contain dyes and tastes good.

Paracetamolantipyretic most commonly used in pediatrics in view of its effectiveness and high safety profile. In the reviews, there are opinions that Rapidol has a more advantageous form of release compared to syrups and suspensions, which, when opened, can be stored for no more than 7 days in the refrigerator, and then unused syrup needs to be poured. Rapidol tablets are stored for 2 years and can be used as needed. Some are not satisfied with the short duration of the drug (4 hours) compared with Nurofen.

Paracetamol does not belong to the group of non-steroidal anti-inflammatory drugs, therefore erosive gastrointestinal lesions and bronchospasm when it is taken are extremely rare. Most often, when taking the drug, itching and rashes are noted. It should be noted that despite the relative safety of any antipyreticsit should be used in children if the fever exceeds the permissible limit (above 38-39.5 ° C) and leads to a violation of the functions of the central nervous system and the cardiovascular system.

Rapidol price where to buy

At the moment, it is not possible to buy Rapidol in pharmacies in Moscow and other cities. Paracetamol for children suspension 200 ml is offered at a price of 112 rubles. up to 134 rubles., Paracetamol tablets 500 mg from 2.6 rubles. up to 5.84 rubles., Efferalgan in effervescent tablets and syrup.

Watch the video: Rapidol (February 2020).

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